What are the effects of CBNO and how does it differ from CBN?
- What is CBNO?
- CBNO vs. CBN: key differences
- Effects and possible benefits of CBNO
- What CBNO products to include in the range?
- Conclusion
CBNO, short for cannabinol-O-acetate, is gaining increasing attention in the cannabis industry. This unique cannabinoid has several specific properties compared to more well-known compounds such as CBD and CBG and offers a variety of applications.
What is CBNO?
CBNO is the acetylated form of CBN, a chemically modified version of this cannabinoid. Although it differs only minimally from CBN at the molecular level, this is enough to make its effects markedly different. The difference is that while CBN is formed by degradation of THC, CBNO is formed by oxidation of CBN.
CBNO vs. CBN: key differences
Both substances have several common features. They are non-psychoactive, share some potential effects (positive effect on sleep), are found in a wide range of products, legal in most countries and are not listed as hazardous substances internationally.
CBNO is a relatively new compound among cannabinoids and therefore may not yet be explicitly regulated in some jurisdictions.
In these cases, it falls under the general cannabinoid legislation, which means that it may be legally available in some areas, even if not yet specifically regulated by local laws.
The difference, however, lies in their potency - the oxidation of CBN to CBNO is said to significantly increase its potential. Some studies report that CBNO can be up to three times more potent than CBN alone.
Effects and possible benefits of CBNO
Research on CBNO is still at an early stage and therefore there is not yet enough scientifically based information on its exact effects. However, as with other cannabinoids, its interaction with the endocannabinoid system is likely to provide potential avenues for therapeutic use.
This system is responsible for regulating many key processes in the body, such as:
- pain perception
- Immunity
- appetite
- sleep quality and mood
CBNO binds to the CB2 receptor, which is mainly associated with the immune system, and unlike THC, does not have a strong effect on the CB1 receptor, which is responsible for psychoactive effects. As a result, CBNO has minimal or no psychoactive effects, making it an attractive choice for possible therapeutic use.
Based on knowledge of CBN and other cannabinoids, as well as user experience, CBNO is predicted to have potential in several areas:
- alleviation of inflammation
- pain relief
- sleep support
- help with stress and tension management
- protection of cells from damage
Anti-inflammatory properties
Some cannabinoids, such as CBN and potentially CBNO, have been found to have anti-inflammatory effects. These substances could be used to treat chronic inflammatory diseases and other related health problems. One major animal study, for example, found that CBN could effectively help treat arthritis due to its anti-inflammatory potential.
Pain relief
Scientific studies suggest that many cannabinoids can act as analgesics. A review study 2015 published in the prestigious medical journal JAMA, including 79 clinical trials, concluded that cannabinoids may be effective in reducing chronic and neuropathic pain.
A more recent study from 2019, focusing on CBN, CBD and CBC, demonstrated the potential of these cannabinoids in reducing muscle sensitization in female rats.
Thus, CBN could provide relief from pain associated with chronic muscle disorders such as temporomandibular dysfunction (pain in the jaw muscles, joints and nerves) and fibromyalgia, without serious side effects. Yet clinical studies have not yet fully proven this theory.
Relaxation and stress relief
Cannabinoids are often associated with relaxing and calming effects, such as relieving stress and anxiety. CBNO is expected to have similar effects due to its similar chemical composition, but further research is needed to confirm these results. For example, CBNO oils and drops could be used to help manage stress and tension.
Sleep aid
In recent years, there has been growing interest in the use of cannabinoids, particularly CBN and CBD, to improve sleep quality. Some research suggests that CBN not only shortens the time it takes to fall asleep, but also helps the body stay asleep longer.
CBNO, especially in its isolated form (which is the purest version of CBNO), could act as a mild sedative, making it suitable for people suffering from insomnia and other sleep disorders. In addition, the isolates allow for precise dosing and are easy to incorporate into a variety of products.
Neuroprotection
Studies to date suggest that cannabinoids also have neuroprotective properties, meaning they could protect nerve cells from degradation. This ability could be used in the treatment of neurodegenerative diseases. These include:
- Parkinson's disease
- Alzheimer's disease
- Huntington's disease
- Multiple sclerosis
Significant results came from a 2022 study by researchers at the Salk Institute, who found that CBN protects neurons from oxidative stress and cell death, which are major contributing factors to the development of Alzheimer's disease. This discovery could lead to new treatment options for Alzheimer's and other similar age-related diseases, according to the researchers.
Which CBNO products to include in the offer?
CBNO can be offered in different forms, with each form differing in the speed of onset, duration and bioavailability of effects. Thus, the choice depends on customer preferences and their requirements for the resulting effect.
Inhalation
Our range includes cartridges of the popular White Cherry/Gelato and Jack the Ripper flavours, which contain 50% CBNO and are particularly appreciated by customers for their intense flavour profile.
In addition, some of the most popular customer products are available, namely the Hawaiian Haze cannabis prerolls, which contain 10% CBNO, CBG pollen and natural terpenes.
CBNO liquids suitable for e-cigarettes as well as CBNO disposable vaporizers are also popular among customers for their ease of use and effectiveness.
CBNO hashish and Raspberry Kush cannabis flowers, known for their distinctive raspberry scent, are also in high demand among customers.
You can also order CBNO distillates from us, which are a pure, concentrated form of cannabinoids (no additional additives or flavours) that are ideal for bulk consumers. These distillates can be used to make other products such as vaporizers, oils and drops.
Edibles
In the edibles segment, we offer CBNO gummies with fruit flavors, each containing 10 mg of CBNO, which can be ordered in packages ranging from 1,000 to 500,000 g. The THC content of these CBNO gummies is below 0.2%, which meets the legal standards of most European countries.
In addition to CBNO, these candies contain classic ingredients such as sugar, glucose syrup and vegetable oil, making them an attractive and well-known form of nutritious food for consumers.
We also offer the possibility to purchase finished products with CBNO not labelled with a specific brand or CBNO raw materials in large volumes for the actual production of products.
Conclusion
CBNO represents a novel cannabinoid with enormous potential. Thanks to its unique chemical structure and wide range of possible effects, it may offer not only an alternative to popular compounds such as CBD and CBN, but also new possibilities for therapeutic use. Although research is still ongoing, early results suggest that CBNO could offer benefits in the areas of pain relief, inflammation reduction, sleep support or stress management. CBNO presents an opportunity to enrich your product range with innovative products that respond to the growing consumer demand for potent and legal cannabinoids.
Author: Pavla Skřivánková
Photo: AI
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